Nizoral Ketoconazole Anti-dandruff Shampoo works by treating the underlying cause of dandruff by restoring your scalp back to its normal healthy stats. A pearlescent luxury shampoo created to take care of dandruff and your hair. Pour it in your hand and Nizoral feels silky soft. The thick, rich lather rinses clean. Use it just twice a week and your hair is shiny, manageable, full of body. And, oh yes, free of dandruff.